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I would disagree with that, for the only thing you need to execute someone is to have the means (Special Forces or Tomahawks) and the position of where the person is located, which should be quite easy given the intelligence gathering of the CIA.
So If you have the means you would only need the will.
Problem you are forgetting is that assassinating a high-profile politician automatically makes him a martyr. That is the problem. Where he falls, thousands will stand up and seek revenge.
I really think you're over estimating special forces & intelligence here. Most dictators have a cadre of bodyguards equal to the best special ops that anyone in the west has (reason being we generally train them). Even the best Delta Force / SAS / SBS / Navy Seal / whatever group will only be able to get so far against a large & well trained elite unit that dictators generally have somewhere, even if the majority of the army is poorly armed and trained.
Tomahawks, agreed are accurate and deadly, but you need to know the location of your target and then pick a time when he isn't hiding in an armoured, underground bunker (and be prepared to admit publically that you did it). The inital plan of the Iraq war was to take out Saddam and his aides, through missile bombardment, but, because noone knew where he was (although the CIA
thought he was in Bagdad) they didn't catch him for months. Tracking people with satellites isn't easy at all & spies are only useful until they get caught (which, with a paranoid dictator happens a lot).
Given what we've seen in Iraq, I doubt the assasination of Saddam would have led to 1000s seeking revenge.
The only effective way to depose a dictator is to invade. Assasination is a complex process that can go wrong in a lot of ways.