It's not that I doubt your veracity, Vampiel, but I do, however doubt the veracity of the links you provided. For instance, let's look at the two WebMD sources you cite. I noticed something at the bottom of each of the pages you linked to. That something is this:
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© 1997–2004 GlaxoSmithKline. All Rights Reserved. This site is intended for US residents only.
WebMD does not endorse any specific product, service, or treatment.
C'mon Vamp. A PR piece by a pharmaceutical company (GlaxoKline) can hardly be considered objective, now can it?
One of the cited pages even admits to something I said, but they use it as a "throwaway" line, in a larger paragraph. My quoted statement:
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And government funded medical R&D typically focuses on the early stages of a drug's development, when the risks are the highest.
And now the quote from the WebMD page. Notice how unimportant they make that early research and development seem:
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The government's primary health research arm, the National Institutes of Health (NIH), and the pharmaceutical companies do play vital and complementary roles in advancing the scientific knowledge and understanding of disease, which assists in the development of new medicines. Most of the government's work, however, is in early research activities that may not lead to specific products.
Hmm, most of the government's research is in the early stages, where the highest rates of risk and failure occur. Isn't that exactly what I said? So again, I ask, if the government is taking on most of the high risk research, why is it that a private company gets to keep all of the reward as if they were taking the risk?
Also, I find this statement in the same article more than a little misleading:
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In fact, as NIH has cited, more than 75% of licensed "inventions" funded by NIH amounted only to "proofs of a concept," such as basic research confirming that HIV is the cause of AIDS. Moreover, an exhaustive study by NIH revealed that of the 47 top-selling medicines in the US, only four had been developed in part with technologies created by NIH funding.
The fact is, this isn't accurate at all. According to
Public Citizen's Congress Watch report, the NIH examined, in 1995, the top 5 selling drugs. Before looking at these drugs, the NIH had no idea what role public funding of research played in the development of these drugs. Their findings?
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§ NIH found that “NIH-funded research played a critical role in drug discovery in each of these cases.” In all, U.S. taxpayer-funded researchers conducted 55 percent of the published research projects leading to the discovery and development of these drugs (and foreign academic institutions 30 percent). “Researchers at U.S. universities and at NIH contributed by discovering basic phenomena and concepts, developing new techniques and assays, and participating in clinical applications of the drugs.”
§ In the case of the hypertension drugs captopril and enalapril, the NIH concluded that the drugs were developed thanks to 14 public U.S. research projects and five foreign academic studies. Only three significant studies were conducted by the drugs’ patent holders, Squibb and Merck.
§ Furthermore, four of the taxpayer-funded studies were deemed “key” and six of the studies were referenced in the industry’s work. The studies sponsored by the patent holders for these two drugs were of less consequence – none were considered “key” by the NIH. In fact, for the five drugs it studied, the NIH deemed only one industry study “key.”
Ok, Vamp, here's my big (sort-of) apology. I may be wrong. If big pharma's numbers are to be believed, they do indeed spend more in research than the government. But not that much more. If you do indeed include from your "Research America" link, the state, local, university and independent research institutes (which undoubtably receive government funding), drug companies spend $49,900,000 on research. All of the government spending, including the states, universities, etc, but not including the private foundations, comes to $40,821,000 a difference of less than $10 million. If that's indeed the case, public funding isn't most of the R&D in this country, but it's still a significant amount, isn't it?
But, can big pharma's numbers be believed? Critics have long maintained that drug companies include in their published research numbers, expenses that should more accurately be included in the marketing and/or operations numbers, to inflate their research numbers as a scare tactic ("No new drugs would be made if it weren't for our R&D sacrifice").
source: Public Citizen.org
http://www.citizen.org/documents/ACFDC.PDFAnd if you think that the pharmaceutical companies perform more research in the form of clinical trials than the government or other public agencies, you'd be wrong again. According to the
governments own website, that keeps track of current and ongoing clinical trials, both those recruiting test subjects and those that don't, the numbers heavily favor the public sector.
For recruiting trials only, drug companies are funding 940 trials. But the public sector is funding 5095 trials. Non-recruiting trials are even more telling: 2,730 drug company trials, compared with 13,541 public funded trials.
The fact is, the public is financing a huge portion of medical research in this country, and then we're getting stuck with the tab on the other side, as well, by paying more for the drugs here than anywhere else in the world. I think it's about time we started seeing some "return" on our investment.